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250 大学院医歯学総合研究科(医) = Graduate School of Medical and Dental Sciences (Medical) >
20 紀要 = Departmental Bulletin Paper >
02 新潟医学会雑誌 = Niigata medical journal >


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Title :遺伝性毛髪疾患
Title alternative :Herediatary Hair Diseases
Authors :下村, 裕
Publisher :新潟医学会
Issue Date :Jul-2011
Journal Title :新潟医学会雑誌
Volume :125
Issue :7
Start Page :347
End Page :351
ISSN :0029-0440
Abstract :Mammalian hair follicle (HF) is a complex structure which consists of several distinct cell layers. The HF is an ectodermal appendage that resides the skin, and unlike other tissues and organs, it possesses the remarkable ability of self renewal and undergoes a hair cycle throughout life. Recent advances in molecular genetics have enabled the identification of numerous genes that are involved in HF morphogenesis and cycling. Furthermore, we and others have recently reported that mutations in some of these genes are associated with hereditary hair diseases in humans, such as autosomal recessive woolly hair and autosomal dominant hypotrichosis simplex. Identification of causative genes for hair diseases strongly and directly suggests crucial roles of these genes in HF morphogenesis, development, and hair growth in humans.
Keywords :hair follicle
woolly hair
Type Local :紀要論文
Language :jpn
Format :application/pdf
URI :http://hdl.handle.net/10191/29194
fullTextURL :http://dspace.lib.niigata-u.ac.jp/dspace/bitstream/10191/29194/1/125(7)_347-351.pdf
Appears in Collections:02 新潟医学会雑誌 = Niigata medical journal

Please use this identifier to cite or link to this item: http://hdl.handle.net/10191/29194