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Title :Adaptive Partial Median Filter for Early CT Signs of Acute Cerebral Infarction
Authors :Lee, Yongbum
Takahashi, Noriyuki
Tsai, Du-Yih
Ishii, Kiyoshi
Publisher :Springer Berlin/Heidelberg
Issue Date :Aug-2007
Journal Title :International Journal of Computer Assisted Radiology and Surgery
Volume :2
Issue :2
Start Page :105
End Page :115
ISSN :1861-6429
Description :Purpose: Detection of early CT signs of infarct in non-enhanced CT image is mandatory in patients with acute ischemic stroke. Loss of the gray-white matter interface at the lentiform nucleus or the insular ribbon has been an important early CT sign of acute cerebral infarction, which affects decisions on thrombolytic therapy. However, its detection is difficult, since the principal early CT sign is subtle hypoattenuation. An image processing method to reduce local noise with edges preserved was developed to improve infarct detection. Rationale: An adaptive partial median filter (APMF) was selected for this application, since the APMF can markedly improve the visibility of the normal gray-white matter interface. APMF should enhance the conspicuity of gray-white matter interface changes due to hypoattenuation that accompanies cerebral infarction. Method: In a criterion referenced performance study using simulated CT images with gray-white matter interfaces, a total of 14 conventional smoothing filters were also used for comparison to validate the usefulness of the proposed APMF. The APMF indicated the highest performance among the compared methods. Then, observer performance study by receiver operator characteristic (ROC) analysis was performed with 4 radiologist observers using a database with 18 abnormal and 33 normal head CT images. Results: The average Az values of ROC curves for all radiologists increased from 0.876 without the APMF images to 0.926 with the APMF images, and this difference was statistically significant (P=0.04). Conclusion: The results from the two observer performance studies demonstrated that APMF has significant potential to improve the diagnosis of acute cerebral infarction using non-enhanced CT images.
Keywords :computer-aided diagnosis (CAD)
acute cerebral infarction
noise reduction
edge preserving
improved median filter
Type Local :学術雑誌論文
Language :eng
URI :http://hdl.handle.net/10191/6246
URL :http://www.springerlink.com/content/120019
fullTextURL :http://dspace.lib.niigata-u.ac.jp/dspace/bitstream/10191/6246/1/05_0001.pdf
DOI :http://dx.doi.org/10.1007/s11548-007-0123-3
Appears in Collections:10 査読済論文 = Postprint

Please use this identifier to cite or link to this item: http://hdl.handle.net/10191/6246